KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PAK6
All Species:
33.33
Human Site:
S494
Identified Species:
52.38
UniProt:
Q9NQU5
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NQU5
NP_001122100.1
681
74869
S494
G
A
L
T
D
I
V
S
Q
V
R
L
N
E
E
Chimpanzee
Pan troglodytes
XP_510301
627
67581
M446
G
E
E
L
W
V
L
M
E
F
L
Q
G
G
A
Rhesus Macaque
Macaca mulatta
XP_001093484
681
74821
S494
G
A
L
T
D
I
V
S
Q
V
R
L
N
E
E
Dog
Lupus familis
XP_544614
968
105825
S781
G
A
L
T
D
I
V
S
Q
V
R
L
N
E
E
Cat
Felis silvestris
Mouse
Mus musculus
Q3ULB5
682
74848
S495
G
A
L
T
D
I
I
S
Q
V
R
L
N
E
E
Rat
Rattus norvegicus
Q62829
544
60692
Q363
E
T
C
M
D
E
G
Q
I
A
A
V
C
R
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515215
639
68748
T458
L
N
E
E
Q
I
A
T
V
C
E
S
V
L
Q
Chicken
Gallus gallus
XP_426393
667
74767
S480
G
A
L
T
D
I
V
S
Q
I
R
L
N
E
E
Frog
Xenopus laevis
NP_001082100
650
73749
T467
G
A
L
T
D
I
V
T
H
T
R
M
N
E
E
Zebra Danio
Brachydanio rerio
XP_001919719
693
77347
S506
G
A
L
T
N
I
V
S
E
T
R
L
S
E
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VXE5
639
69601
R458
T
D
I
V
T
H
S
R
M
D
E
E
Q
I
A
Honey Bee
Apis mellifera
XP_001122147
624
70155
M443
D
I
V
T
H
S
R
M
D
E
N
Q
I
A
T
Nematode Worm
Caenorhab. elegans
Q17850
572
63863
I391
C
Q
M
E
D
G
I
I
A
A
V
C
R
E
V
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q03497
939
102344
T707
G
S
L
T
D
V
V
T
H
C
I
L
T
E
G
Red Bread Mold
Neurospora crassa
Q7RZD3
954
103773
T761
G
S
L
T
D
V
V
T
F
N
I
M
T
E
G
Conservation
Percent
Protein Identity:
100
52.7
98.5
66.4
N.A.
92.5
30.6
N.A.
62.2
75.9
46.7
52.5
N.A.
44.3
44.9
29.8
N.A.
Protein Similarity:
100
60.7
98.9
67.6
N.A.
95.5
48.4
N.A.
69.9
82.3
61.6
64.5
N.A.
57.5
57.5
47.2
N.A.
P-Site Identity:
100
6.6
100
100
N.A.
93.3
13.3
N.A.
6.6
93.3
73.3
73.3
N.A.
0
6.6
13.3
N.A.
P-Site Similarity:
100
26.6
100
100
N.A.
100
20
N.A.
20
100
86.6
93.3
N.A.
6.6
13.3
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
25.5
28
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
43.1
41.6
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
46.6
40
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
66.6
66.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
47
0
0
0
0
7
0
7
14
7
0
0
7
14
% A
% Cys:
7
0
7
0
0
0
0
0
0
14
0
7
7
0
0
% C
% Asp:
7
7
0
0
67
0
0
0
7
7
0
0
0
0
0
% D
% Glu:
7
7
14
14
0
7
0
0
14
7
14
7
0
67
54
% E
% Phe:
0
0
0
0
0
0
0
0
7
7
0
0
0
0
0
% F
% Gly:
67
0
0
0
0
7
7
0
0
0
0
0
7
7
14
% G
% His:
0
0
0
0
7
7
0
0
14
0
0
0
0
0
0
% H
% Ile:
0
7
7
0
0
54
14
7
7
7
14
0
7
7
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
7
0
60
7
0
0
7
0
0
0
7
47
0
7
0
% L
% Met:
0
0
7
7
0
0
0
14
7
0
0
14
0
0
0
% M
% Asn:
0
7
0
0
7
0
0
0
0
7
7
0
40
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
7
0
0
7
0
0
7
34
0
0
14
7
0
7
% Q
% Arg:
0
0
0
0
0
0
7
7
0
0
47
0
7
7
0
% R
% Ser:
0
14
0
0
0
7
7
40
0
0
0
7
7
0
0
% S
% Thr:
7
7
0
67
7
0
0
27
0
14
0
0
14
0
7
% T
% Val:
0
0
7
7
0
20
54
0
7
27
7
7
7
0
7
% V
% Trp:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _